X

Download Big Cancer Prostate Cancer PowerPoint Presentation

SlidesFinder-Advertising-Design.jpg

Login   OR  Register
X


Iframe embed code :



Presentation url :

Home / Health & Wellness / Health & Wellness Presentations / Big Cancer Prostate Cancer PowerPoint Presentation

Big Cancer Prostate Cancer PowerPoint Presentation

Ppt Presentation Embed Code   Zoom Ppt Presentation

PowerPoint is the world's most popular presentation software which can let you create professional Big Cancer Prostate Cancer powerpoint presentation easily and in no time. This helps you give your presentation on Big Cancer Prostate Cancer in a conference, a school lecture, a business proposal, in a webinar and business and professional representations.

The uploader spent his/her valuable time to create this Big Cancer Prostate Cancer powerpoint presentation slides, to share his/her useful content with the world. This ppt presentation uploaded by onlinesearch in Health & Wellness ppt presentation category is available for free download,and can be used according to your industries like finance, marketing, education, health and many more.

About This Presentation

Slide 1 - Possible Loci Linked to Prostate Cancer By Angela Marks Biochemistry/Molecular Biology Seminar
Slide 2 - The Facts about Prostate Cancer Most common malignancy among U.S. men Estimated 179,300 new cases in 1999 1 in 5 lifetime probability of diagnosis in U.S. men African Americans have 34% higher incidence rate and 2 times higher mortality rate than white Americans Asian men have lowest incidence rate Estimated 37,000 deaths in 1999 in U.S.
Slide 3 - The Prostate Gland Male sex gland Size of a walnut Helps control urine flow Produces fluid component of semen Produces Prostate Specific Antigen (PSA) and Acid Phosphatase
Slide 4 - Four Areas of the Prostate Transition Zone Peripheral Zone Anterior Zone Central Zone www.prostatematters.com
Slide 5 - Factors Increasing Risk of Prostate Cancer Age Lifestyle Hormones Race Genetics
Slide 6 - Genetic mutations in Prostate Cancer? Germline mutations Methylation changes Loss of GSTp expression Androgen receptor - short . tandem repeats (Xq11-12) Chromosome 16q loss PTEN mutation (10q23) p53 inactivation (17p)
Slide 7 - Early event in development of prostate cancer CpG islands within promoter regions and open reading frames of growth regulatory genes Glutathione S transferase -pi (GSTp) scavenges free radicals Loss may be caused by methylation GSTp absent in almost every prostate tumor GSTp may be only thing stopping prostate cancer Small polymorphic CAG repeats (microsatellites) associated with transactivation activity Inverse relationship between CAG repeats and prostate cancer 16q is sight of tumor suppressor gene, E-cadherin Loss of E-cad increases disease progression
Slide 8 - PTEN phosphatase functions as a tumor suppressor by negatively regulating cell interactions Acts as a gate to regulate the movement of growth-regulating signals G:C to A:T transition mutation Inactivation of p53 results in loss of DNA repair
Slide 9 - Possible Germline Mutations Hereditary Prostate Cancer 1 gene (HPC1) on chromosome 1q24-q25 Predisposing locus for early-onset prostate cancer (PCAP) on 1q42.2-q43 Hereditary prostate cancer locus (HPCX) on Xq27-q28 Rare PC-Brain Cancer Susceptibility locus (CAPB) on 1q36
Slide 10 - Future Research Comparative Genomic Hybridization (CGH) Loss of . Heterozygosity . (LOH) Linkage Analysis Pictures: http://core1.joslab.harvard.edu, http://www.vgl.ucdavis.edu/service/canine/micros.htm, and http://amba.charite.de/cgh
Slide 11 - Clone those genes to better understand function Will expand on knowledge of non-hereditary causes of prostate cancer Allow for more accurate diagnoses and better treatments
Slide 12 - Genome-wide search for susceptibility loci
Slide 13 - References Barry, R. et al. Grant proposal. Mayo Clinic. 1998. Berthon, P. et al. Predisposing Gene for Early-Onset Prostate Cancer, Localized on Chromosome 1q42.2-43. Am J. Hum Genet 62:1416-1424, 1998. Capcure. The Association for the Cure of Cancer of the Prostate. Http://www.capcure.org Dahiya, R., et al. High Frequency of Genetic Instability of Microsatellites in Human Prostatic Adenocarcinoma. Int J. Cancer 72: 762-7, 1997. Gronberg, H., et al. Early Age at Diagnosis in Families Providing Evidence of Linkage to the Heredita Postate Cancer Locus (HPC1) on Chromosome 1. Cancer Research 57, 4707-9, 11/1/97 Irvine, RA., et al. The CAG and GGC microsatellites of the androgen receptor gene are in linkage disequilibrium in men with prostate cancer. Cancer Research 1;55(9): 1937-40, 1995. Joslin Diabetes Center, DNA Core Facility. Microsatellites. http://core1.joslab.harvard.edu/core/microsats.html. Kang, HY., et al. Cloning and Characterization of Human Prostate Coactivator ARA54, a Novel Protein that Associates with the Androgen Receptor. J Biol Chem 274(13): 8570-76, 03/26/99. Li, L., et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 275: 1943-46, 1997.
Slide 14 - References Navone, NM, et al. p53 mutations in prostate cancer bone metastases suggest that selected p53 mutants in th eprimary site define foci with metastatic potential. J Urol 161(1):304-8, 1/99. Novahealth@earthlink.net www.prostatematters.com 1998 Pienta, K., Goodson, J., & Esper, P. Epidemiology of Prostate Cancer: Molecular and Environmental Clues. http://www.cancer.med.umich.edu/prostcan/articles/clues.html Smith, J, et al. Major Susceptibility Locus for Prostate Cancer on Chromosome 1 Suggested by a Genome-Wide Search. Science 274: 1371-4, 11/22/96. Veterinary Genetics Laboratory, School of Veterinary Medicine University of California, Davis. Microsatellites. http://www.vgl.ucdavis.edu/service/canine/micros.htm 12/30.97 Wolf, G. University Hospital Charite Institute of Pathology. http://amba.charite.de/cgh 1/15/99 Xu, J., et al. Evidence for a prostate cancer susceptibility locus on the X chromosome. Nature Genet 20: 175-179, 1998.
 

Frequently Asked Questions

> About SlidesFinder?

Slidesfinder is a website that allows users to upload and share their PowerPoint presentations online. It provides a platform for individuals and businesses to share their ideas and knowledge through presentations, and for others to view and download these presentations for educational or professional purposes.
Slidesfinder offers a wide range of presentation topics and categories, including business, education, science, technology, health, and more. Users can also search for presentations using keywords, tags, or by category. The website provides tools to create professional presentations with rich media, animations, and graphics.



One of the key features of Slidesfinder is its user-friendly interface, which allows users to easily upload, view, and share presentations. Users can also embed their presentations in their websites or blogs using the website's embed code feature.
Slidesfinder also offers premium services, such as the ability to create private presentations and to download presentations in high-quality formats. However, the basic features of Slidesfinder are free to use, making it accessible to anyone who wants to share their ideas and knowledge through presentations.

> How do I register with SlidesFinder?

Go to registration page (you can see signup link on top of website page) https://www.slidesfinder.com/signup . If you have facebook/gmail account them just click on SIGN IN WITH FACEBOOK OR SIGN IN WITH GOOGLE button, by this you will be a registered member of slidesfinder without filling any form, required detail automatically will be fatch from your account. If you do not a Facebook account, then click on "Signup". Fill all required fields and you will be a registered member of slidesfinder.

> Is slidesfinder account confirmation is mandatory?

Yes it is mandetory to active your account to login.

> Do I need to signup/login on SlidesFinder before uploading a PowerPoint presentation?

Yes, you need to login with your account before uploading presentation. Your username will be displayed on your uploaded presentation. Your registered email id is needed for sending your stats of uploaded presentation.

Slidesfinder is a sharing website for PowerPoint presentations search and share. Find your interest in the form of powerpoint presentations on slidesfinder and save your valuable time . On Slidesfinder you get presentations from our huge library of professional ppt presentations. We believe in making your search INFORMATIVE and FUN. Find your best ppt presentation from a pool of PowerPoint presentations stacked under important industry categories like business & management, heath & Wellness,eduction & training etc. We provide unique informative PowerPoint presentation for marketers, presenters and educationists. These professional PowerPoint presentations are uploaded by professionals from across numerous industry segments.These ppt presentations are available for FREE download.

Not just finding your interest, but facilitate you broadcast your interest. We have created this platform for easy sharing of PowerPoint presentations, ensuring that these presentations get maximum exposure. Create your slidesfinder account and upload PowerPoint presentations for free, share on social media platforms and BUILD YOUR CROWD WITH PRESENTATION !!

The Great Buddha says, "Share your knowledge.It’s a way to achieve immortality"! So, start sharing knowledge and we are here to make that immortal !!

© 2013-2024 SlidesFinder. All rights reserved.

Re-productivity of content are not allowed. Without prior written permission from author, commercial use of any content is illegal.